Expression quantitative trait loci (eQTLs) are regions of the genome containing DNA sequence variants that influence the expression level of one or more genes. PancanQTL aims to comprehensively provide cis-eQTLs (SNPs affect local gene expression) and trans-eQTLs (SNPs affect distant gene expression) in 33 cancer types from The Cancer Genome Atlas (TCGA).
In PancanQTL, users can:
Browse or search cis-eQTLs and trans-eQTLs across different cancer types;
Browse or search eQTLs associated with patient overall survival across different cancer types;
Browse or search eQTLs in GWAS linkage disequilibrium (LD) regions;
Jing Gong, Shufang Mei, Chunjie Liu, Yu Xiang, Youqiong Ye, Zhao Zhang, Jing Feng, Renyan Liu, Lixia Diao, An-Yuan Guo, Xiaoping Miao* and Leng Han*. Nucleic Acids Research.(2018)